Brain Research                          Pharma
  Contract Research Organisation using Electrophysiological Technologies

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EEG signal
Preclinical Drug Profiling
Field potentials recorded from the depth of the brain contain information on ion channel activities, neurotransmitter actions and determine behaviour. On an intermediate level between molecular events and behaviour, frequency analysis of these potentials provide solid information on the effectiveness of drugs. A huge data base of more than 200 compounds serves as reference (Please see flyer "Drug profiling .. for further information)

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Primary Nervous Tissue Culture with electrically active neurons.
Clinical Studies
Source density analysis of the EEG provides similar information as field potentials in deeper brain structures. Symphony of neurotransmitter activity is mirrored in particular frequencies and determine cognition, emotion and motor activities. This non-invasive technology allows for objective determination of surrogate parameters of clinical drug action (Please double click picture to see real time brain mapping).

Neuroleptic and anticonvulsant drugs
Analgesic and sedative drugs
Antidepressant and narcotic drugs
Drug profiling by means of discriminant analysis
Surrogate parameters for cognition
Research into emotion
Research into sleep

                              CEO
: Ingrid K. Keplinger-Dimpfel 

Clinical  Consulting: Dr. Winfried Wedekind  
Scientific Consulting: Prof. Dr. Wilfried Dimpfel

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